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The most popular ingredients for liver protection supplements.

As we know liver is one of the human body the largest and most important organs. It likes a natural filter that store and releases energy from foods, catches the “gunk” of blood, and removes toxins and wastes from the cycle system.

Literally, do you know how does the liver work?

The liver eventually processes everything we eat, after digestion, it gets through our bloodstream to the liver for filtering. The liver breaks down fat to release energy, it produces a yellow-green substance called bile to help our body break down and absorb fat.

The liver is also involved in sugar metabolism, it pulls glucose from our blood and stores it in the form of glycogen.Anytime our blood sugar level dips, the liver releases glycogen to keep the levels steady. Also, Alcohol, medications, and other toxins make their way to the liver, they are pulled from the blood, and then the liver either cleans up these substances or removes them into excreta.

As a human body cleaner, it is quite important to keep our liver healthy and running perfectly. In addition to a good lifestyle and healthy eating habits, some liver care supplements are very popular. Many of the liver supplements on the market contain a combination of these ingredients:


  • L-Glutathione

  • NAC

  • Choline Bitartrate

  • Inositol

  • Zinc glycinate

  • Milk Thistle Extract

  • Artichoke Leaf Extract

  • Dandelion Root Extract

  • Turmeric Root Extract

Let’s break down each ingredient by the research.

TUDCA (tauroursodeoxycholic acid) is a unique bile acid found in small amounts in the overall composition of bile. It has been used in Chinese medicine for thousands of years as a digestive aid and liver support, and now we are able to produce it as a supplement.TUDCA’s many benefits include digestive support (especially for fats), promoting liver and kidney function, brain health, cellular support, and eye health.


Glutathione is an antioxidant produced in cells. It’s comprised largely of three amino acids: glutamine, glycine, and cysteine. Glutathione levels in the body may be reduced by a number of factors, including poor nutrition, environmental toxins, and stress. Its levels also decline with age.

Glutathione has been shown to improve protein, enzyme, and bilirubin levels in the blood of individuals with alcoholic and nonalcoholic chronic fatty liver disease. A study reported that glutathione was most effective when given to people with fatty liver disease intravenously, in high doses

The liver is susceptible to oxidative stress and inflammation from continuous exposure to alcohol, a fatty diet, certain medications, or environmental pollution. These conditions can lead to liver damage and disease.3 Because the liver is the primary organ of detoxification, it is important that the liver is provided optimal antioxidant capacity.

Is NAC good for your liver? NAC liver support centers around maintaining this antioxidant capacity, thereby protecting the hepatocytes (liver cells). Because of NAC’s role in producing glutathione, it supports the reduction of oxidative insults to the liver from foreign substances. In addition, through the donation of its sulfur, NAC supports the normal detoxification function of the liver as it breaks down and eliminates toxic substances.

Choline promotes a healthy liver by enabling it to metabolize fatty deposits. It works with inositol to help emulsify fats and cholesterol so that they do not settle on artery walls or within the gallbladder. Choline has the ability to emulsify dietary lipids (fats), to prevent their deposits in blood vessels. Necessary for the synthesis of acetylcholine which transmits impulses from one nerve to another and plays a critical role in memory function.


Myo-inositol supplementation improves cardiometabolic factors, anthropometric measures, and liver function in obese patients with non-alcoholic fatty liver disease. Usually, inositol is stacked with Choline Bitartrate.

Zinc glycinate

Zinc Glycinate is a fully reacted, proprietary amino acid chelate formulated for enhanced absorption. As an essential mineral, zinc serves catalytic, structural, and regulatory functions in the body. Zinc ultimately supports immune and neurological function, growth, taste acuity, nutrient metabolism, and reproductive health.

Except above compounds supplement, there are four popular herb extracts that have been used in most liver protection supplements also, herbal extracts have been trusted as their natural function with fewer side effects.

Milk thistle is an herbal remedy derived from the milk thistle plant, also known as Silybum marianum. This prickly plant has distinctive purple flowers and white veins, which traditional stories say were caused by a drop of the Virgin Mary’s milk falling onto its leaves. The active ingredients in milk thistle are a group of plant compounds collectively known as silymarin.

Its herbal remedy is known as milk thistle extract. Milk thistle extract has a high amount of silymarin (between 65–80%) that has been concentrated from the milk thistle plant. The silymarin extracted from milk thistle is known to have antioxidant, antiviral, and anti-inflammatory properties (2, 3, 4).

Artichoke leaf has antioxidant properties. Studies suggest that it may protect the liver. Research done in animals shows it may help liver cells regenerate.In studies done in 2016 and 2018 of people with nonalcoholic fatty liver disease, artichoke leaf reduced markers of liver damage compared with placebo. However, the clinical benefits of artichoke leaf supplementation remain to be seen.

Dandelion (Taraxacum officinale) is a plant often regarded as a weed but one that may offer health benefits. It is said to have anti-inflammatory, antibacterial, and antioxidant properties.

Dandelion root benefits are often promoted by naturopaths and other alternative practitioners who contend that dandelion acts as a diuretic ("water pill") or potentially boosts the immune system to help fight infections. Its benefits are touted in arthritis, liver disease, diabetes, obesity, and even cancer.

Dandelion extract is applied to liver inflammation and congestion. As one of the most effective detoxification herbs, it acts as a filter for toxins and waste from the bloodstream, gallbladder, liver, and kidneys. It stimulates bile production and helps the body get rid of excess water produced by the damaged liver.

Curcumin is the major bioactive component found in the roots of turmeric (Curcuma longa), a plant belonging to the ginger family. Turmeric Root Extract contains 95% curcuminoids, the active ingredient in turmeric. Turmeric contributes to digestive comfort and better fat digestion. Turmeric helps support normal liver function.

Other ingredients

In addition to milk thistle, artichoke, and dandelion, liver supplements differentiate themselves by adding a blend of other ingredients. This can include things like:

Beet Root Extract

Hawthorn Berry Extract

Chanca Piedra Extract

Contact sales@scbiochem for free samples anytime.

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